TNF alpha Antikörper

Produktnummer ABIN6963896

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch TNF alpha in ELISA und ELISpot. Er zeigt eine Reaktivität gegenüber Maus und wurde in 5+ Publikationen erwähnt.

Kurzübersicht für TNF alpha Antikörper (ABIN6963896)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TNF alpha Antikörper ist unkonjugiert

Applikation: ELISA, ELISpot

Klon: MT1C8-23C9

Produktdetails anti-TNF alpha Antikörper

Spezifität: Native and recombinant TNF-α

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant mouse TNF-alpha

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-TNF alpha Antikörper (ABIN6963896)

Chen, Chen, Ren, Xia, Zhu, Liu, Zhang, Tang, Sun, Liu, Dong: "Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease." in: Kidney international, Vol. 96, Issue 2, pp. 409-420, (2020) (PubMed).

Li, Yan, Huang, Chi, Xu, Li, Liu, Feng, Wang, Zhao, Yang, Xia: "Characterization of the Immune Response of MERS-CoV Vaccine Candidates Derived from Two Different Vectors in Mice." in: Viruses, Vol. 12, Issue 1, (2020) (PubMed).

Li, Chi, Huang, Yan, Zhang, Liu, Wang, Li, Zhang, Mo, Jin, Wang, Feng, Wang, Bi, Wang, Sun, Gao, Zhao, Yang, Xia: "A Novel Bacterium-Like Particle Vaccine Displaying the MERS-CoV Receptor-Binding Domain Induces Specific Mucosal and Systemic Immune Responses in Mice." in: Viruses, Vol. 11, Issue 9, (2020) (PubMed).

Chida, Hara, Yano, Uchiyama, Das, Takahashi, Miyata, Tomioka, Ito, Kido, Sakaguchi: "Prion protein protects mice from lethal infection with influenza A viruses." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007049, (2018) (PubMed).

Abbassi-Daloii, Yousefi, Sekhavati, Tahmoorespur: "Impact of heat shock protein 60KD in combination with outer membrane proteins on immune response against Brucella melitensis." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 126, Issue 1, pp. 65-75, (2018) (PubMed).

Details zu TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Andere Bezeichnung: TNFA

Gen-ID: 21926

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome